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Limitations in next-generation sequencing-based genotyping of breast cancer polygenic risk loci – European Journal of Human Genetics

  Missing places and ability to convert to hg38 For the four BC PRS loci, no variants were listed at the specified genomic position in gnomAD version 2.1.1, namely rs572022984, rs113778879, rs73754909, and rs79461387. gnomAD v3.1.2 also reported no variants for three of these four loci for the corresponding loci in hg38 defined by dbSNP….

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As China's moon ambitions explode, it admits it is in a moon race with the United States.

As China’s moon ambitions explode, it admits it is in a moon race with the United States.

  “In the historical context of the period, the competition to demonstrate superior political power destabilized lunar exploration,” the plan states. It can be predicted that in the next 20 to 30 years, China’s International Lunar Research Station and US Artemis Program It will compete in terms of technology and operational efficiency at the same…

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Bathe, be careful: Britain's beaches and rivers have a sewage problem.  It has infiltrated the election debates

Bathe, be careful: Britain’s beaches and rivers have a sewage problem. It has infiltrated the election debates

  HENLEY-ON-THAMES, England — Endurance swimmer Joanne Fennelly dreads cold water and long distances, and swims in nature year-round. But he takes extra precautions in his backyard. The River Thames is one of the many waterways in the UK that have been polluted by sewage and agricultural pollution. “If it looks good, if it smells…

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Characteristics of large clusters of HIV-1 transmission in Victoria, Australia.  (a) Distribution of samples for molecular transport groups.  (B–E) Summary of proportions of different genders (B), risk groups (C), SDRM (D), age groups (E), possible site of acquisition (F) and subtype or CRF (G) in the main groups the transfer .  (H) Distribution of the number of CD4+ T cells in the main transfer groups.  Boxplots show the median and IQR, with whiskers representing the highest and lowest values ​​within 1.5 × IQR of the upper and lower quartiles, and dots representing outliers.  (I) Distribution of links of each node in the main transmission groups.  Box plots show median and interquartile range (IQR), formatted as above.

Innovative genetic analysis maps HIV transmission in Victoria with meaningful community engagement

  By mapping transmission and identifying groups of people at risk of HIV infection, a study examining HIV cases reported in Victoria between 2000 and 2020 illustrates a new approach that could make public health efforts more timely and effective. In a study that Lancet Western Pacific Regional Health, Researchers used a technique called molecular…

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A James Webb Telescope image of the center of the Milky Way showing intersecting red stars and blue filaments of gas.

The “immortal” stars at the center of the Milky Way may have an endless source of energy, study suggests.

A strange cluster of stars orbiting the violent center of the Milky Way could become “immortal” by constantly capturing and destroying dark matter particles in their cores, a new study suggests. Using computer simulations of the evolution of stars, researchers found that dark matter Particles attracted by the gravity of these stars may repeatedly collide…

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